Complementary DNA for 12-Kilodalton B Cell Growth Factor: Misassigned
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چکیده
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References and Notes Complementary Dna for 12-kilodalton B Cell Growth Factor: Misassigned 629
teractions produced by the optical triggers are insufficient to do this. These optical triggers do, however, provide a unique opportunity to investigate the nanosecondmicrosecond dynamics of the unfolded protein prior to surmounting the free energy barrier that separates the unfolded structures from the native state (9). Chi-Kin VChan James \/Hofrichter William A. Eaton Laboratory of Chemical P...
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Insulin-like growth factors I and II (IGF-I and IGF-II) are actively involved in neuroblastoma cell growth. In all biological fluids, they are noncovalently bound to high-affinity binding proteins. At least six species of these IGF-binding proteins (IGFBPs) have been identified, but their precise roles remain unclear. One of them, IGFBP-6, is produced by neuroblastoma cells in culture under cer...
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The importance of murine monokines and lymphokines in T cell immune responses has been emphasized by the development o f T cell cloning technology (1) and the identification of cloned tumor lines that respond to or secrete these factors (2, 3). Such studies have shown that the monokine interleukin 1 (IL-1) 1 induces certain T cells to secrete interleukin 2 (IL-2), and that this lymphokine can m...
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Namalva, a human B cell lymphoma line, produced a factor with a molecular weight of approximately 60,000 which enhanced the proliferation of normal activated human B lymphocytes. The factor also enhanced the proliferation of certain B cell lines. It can be distinguished physiologically and biochemically from other lymphokines known to enhance B cell proliferation, namely, interleukin (IL) 1, IL...
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Human T hybridomas secreting B cell growth factors (BCGF) and B cell differentiation factor (BCDF) have been established. Hybrid clones 77-A, 94-C, and 98-F secreted BCGF that induced proliferation of anti-IgM-stimulated normal B cells. The culture supernatant from 77-A cells could also maintain continuous proliferation of colony-forming B cells, but the factor from 94-C could not. The addition...
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ژورنال
عنوان ژورنال: Science
سال: 1996
ISSN: 0036-8075,1095-9203
DOI: 10.1126/science.274.5287.631a